Pesquisa | Portal de Pesquisa da BVS

1.

Arginine reprograms metabolism in liver cancer via RBM39.

Mossmann, Dirk; Müller, Christoph; Park, Sujin; Ryback, Brendan; Colombi, Marco; Ritter, Nathalie; Weißenberger, Diana; Dazert, Eva; Coto-Llerena, Mairene; Nuciforo, Sandro; Blukacz, Lauriane; Ercan, Caner; Jimenez, Veronica; Piscuoglio, Salvatore; Bosch, Fatima; Terracciano, Luigi M; Sauer, Uwe; Heim, Markus H; Hall, Michael N.

Cell ; 186(23): 5068-5083.e23, 2023 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-37804830

2.

mTOR substrate phosphorylation in growth control.

Battaglioni, Stefania; Benjamin, Don; Wälchli, Matthias; Maier, Timm; Hall, Michael N.

Cell ; 185(11): 1814-1836, 2022 05 26.

Artigo em Inglês | MEDLINE | ID: mdl-35580586

3.

An Amazing Turn of Events.

Hall, Michael N.

Cell ; 171(1): 18-22, 2017 Sep 21.

Artigo em Inglês | MEDLINE | ID: mdl-28888325

4.

Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis.

Park, Sujin; Mossmann, Dirk; Chen, Qian; Wang, Xueya; Dazert, Eva; Colombi, Marco; Schmidt, Alexander; Ryback, Brendan; Ng, Charlotte K Y; Terracciano, Luigi M; Heim, Markus H; Hall, Michael N.

Mol Cell ; 82(22): 4246-4261.e11, 2022 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-36400009

5.

mTORC1: turning off is just as important as turning on.

Benjamin, Don; Hall, Michael N.

Cell ; 156(4): 627-8, 2014 Feb 13.

Artigo em Inglês | MEDLINE | ID: mdl-24529368

6.

The search for antiaging interventions: from elixirs to fasting regimens.

de Cabo, Rafael; Carmona-Gutierrez, Didac; Bernier, Michel; Hall, Michael N; Madeo, Frank.

Cell ; 157(7): 1515-26, 2014 Jun 19.

Artigo em Inglês | MEDLINE | ID: mdl-24949965

7.

More writing: mTORC1 promotes m⁶A mRNA methylation.

Shetty, Sunil; Hall, Michael N.

Mol Cell ; 81(10): 2057-2058, 2021 05 20.

Artigo em Inglês | MEDLINE | ID: mdl-34019785

8.

The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1.

Böhm, Raphael; Imseng, Stefan; Jakob, Roman P; Hall, Michael N; Maier, Timm; Hiller, Sebastian.

Mol Cell ; 81(11): 2403-2416.e5, 2021 06 03.

Artigo em Inglês | MEDLINE | ID: mdl-33852892

9.

Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.

Thedieck, Kathrin; Holzwarth, Birgit; Prentzell, Mirja Tamara; Boehlke, Christopher; Kläsener, Kathrin; Ruf, Stefanie; Sonntag, Annika Gwendolin; Maerz, Lars; Grellscheid, Sushma-Nagaraja; Kremmer, Elisabeth; Nitschke, Roland; Kuehn, E Wolfgang; Jonker, Johan W; Groen, Albert K; Reth, Michael; Hall, Michael N; Baumeister, Ralf.

Cell ; 154(4): 859-74, 2013 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-23953116

10.

TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes.

Shetty, Sunil; Hofstetter, Jon; Battaglioni, Stefania; Ritz, Danilo; Hall, Michael N.

EMBO J ; 42(5): e112344, 2023 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-36691768

11.

Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8⁺ T Cells.

Bantug, Glenn R; Fischer, Marco; Grählert, Jasmin; Balmer, Maria L; Unterstab, Gunhild; Develioglu, Leyla; Steiner, Rebekah; Zhang, Lianjun; Costa, Ana S H; Gubser, Patrick M; Burgener, Anne-Valérie; Sauder, Ursula; Löliger, Jordan; Belle, Réka; Dimeloe, Sarah; Lötscher, Jonas; Jauch, Annaïse; Recher, Mike; Hönger, Gideon; Hall, Michael N; Romero, Pedro; Frezza, Christian; Hess, Christoph.

Immunity ; 48(3): 542-555.e6, 2018 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-29523440

12.

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition.

Borenäs, Marcus; Umapathy, Ganesh; Lind, Dan E; Lai, Wei-Yun; Guan, Jikui; Johansson, Joel; Jennische, Eva; Schmidt, Alexander; Kurhe, Yeshwant; Gabre, Jonatan L; Aniszewska, Agata; Strömberg, Anneli; Bemark, Mats; Hall, Michael N; Eynden, Jimmy Van den; Hallberg, Bengt; Palmer, Ruth H.

Proc Natl Acad Sci U S A ; 121(1): e2315242121, 2024 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-38154064

13.

Making new contacts: the mTOR network in metabolism and signalling crosstalk.

Shimobayashi, Mitsugu; Hall, Michael N.

Nat Rev Mol Cell Biol ; 15(3): 155-62, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24556838

14.

Activation of mTORC2 by association with the ribosome.

Zinzalla, Vittoria; Stracka, Daniele; Oppliger, Wolfgang; Hall, Michael N.

Cell ; 144(5): 757-68, 2011 Mar 04.

Artigo em Inglês | MEDLINE | ID: mdl-21376236

15.

An amino acid shuffle activates mTORC1.

Cohen, Adiel; Hall, Michael N.

Cell ; 136(3): 399-400, 2009 Feb 06.

Artigo em Inglês | MEDLINE | ID: mdl-19203575

16.

The protein histidine phosphatase LHPP is a tumour suppressor.

Hindupur, Sravanth K; Colombi, Marco; Fuhs, Stephen R; Matter, Matthias S; Guri, Yakir; Adam, Kevin; Cornu, Marion; Piscuoglio, Salvatore; Ng, Charlotte K Y; Betz, Charles; Liko, Dritan; Quagliata, Luca; Moes, Suzette; Jenoe, Paul; Terracciano, Luigi M; Heim, Markus H; Hunter, Tony; Hall, Michael N.

Nature ; 555(7698): 678-682, 2018 03 29.

Artigo em Inglês | MEDLINE | ID: mdl-29562234

17.

Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis.

Frei, Irina C; Weissenberger, Diana; Müller, Christoph; Hall, Michael N; Shimobayashi, Mitsugu.

Am J Physiol Endocrinol Metab ; 324(6): E589-E598, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-37166264

18.

Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model.

Suter, Polina; Dazert, Eva; Kuipers, Jack; Ng, Charlotte K Y; Boldanova, Tuyana; Hall, Michael N; Heim, Markus H; Beerenwinkel, Niko.

PLoS Comput Biol ; 18(9): e1009767, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36067230

19.

Loss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAs.

Liko, Dritan; Rzepiela, Andrzej; Vukojevic, Vanja; Zavolan, Mihaela; Hall, Michael N.

Proc Natl Acad Sci U S A ; 117(3): 1524-1532, 2020 01 21.

Artigo em Inglês | MEDLINE | ID: mdl-31919282

20.

Novel roles of mTORC2 in regulation of insulin secretion by actin filament remodeling.

Blandino-Rosano, Manuel; Scheys, Joshua O; Werneck-de-Castro, Joao Pedro; Louzada, Ruy A; Almaça, Joana; Leibowitz, Gil; Rüegg, Markus A; Hall, Michael N; Bernal-Mizrachi, Ernesto.

Am J Physiol Endocrinol Metab ; 323(2): E133-E144, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35723227

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